Bulletin of mathematical analysis and applications

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We observed significant differences between outcomes in patients by time of transplant, presence of chronic graft-versus-host disease, and remission status. Large multicenter studies are needed to assess less toxic conditioning regimens with fewer adverse effects in these patients. Arterial Stiffness Use for Early Monitoring of Cardiovascular Adverse Events due to Anthracycline Chemotherapy in Breast Cancer Patients. Recent studies seek to identify methods that can early detect cardiological and vascular changes as a strategy to decrease the incidence of cardiovascular comorbidities.

OBJECTIVE: To evaluate the role of arterial stiffness measurement in the monitoring of doxorubicin and cyclophosphamide-induced cardiotoxicity in breast cancer patients. METHODS: Prospective longitudinal study in 24 breast cancer patients undergoing treatment with doxorubicin and cyclophosphamide. The left bulletin of mathematical analysis and applications ejection fraction was also evaluated by Doppler echocardiography (pre-chemotherapy and after the fourth chemotherapy cycle).

RESULTS: Patients had a mean age of 52. There was no significant difference between the hemodynamic parameters evaluated by the oscillometric method or in the left ventricular ejection fraction in the different evaluated periods. Related: Breast Cancer Doxorubicin Campone M, Lacroix-Triki M, Roca L, et al.

UCBG 2-08: 5-year efficacy results from the UNICANCER-PACS08 randomised phase III trial of adjuvant treatment editorial manager FEC100 and then either docetaxel or ixabepilone in patients with early-stage, poor prognosis breast cancer.

We boehringer ingelheim gmbh international whether replacing docetaxel with ixabepilone would increase 5-year disease-free survival (DFS).

Baseline characteristics were balanced between arms. Median follow-up was 66. The benefit of ixabepilone in subgroups (patients with TNBC and grade II-III lymphocytic infiltration) requires further evaluation. Related: Breast Cancer Docetaxel Epirubicin Fluorouracil Schiavetti A, Pedetti V, Varrasso G, et al. Bulletin of mathematical analysis and applications investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for childhood sarcoma.

METHODS: A cross-sectional single center study was performed. Outcomes included estimating glomerular bulletin of mathematical analysis and applications rate (eGFR), albuminuria, glycosuria, serum phosphate and bulletin of mathematical analysis and applications, tubular reabsorption phosphate (TRP), chronic kidney disease (CKD) according to the "Kidney Disease: Improving Global Outcomes" (KDIGO) guidelines and blood pressure (BP).

Renal impairment was detected in four cases (13. In the whole cohort of sarcoma survivors, hypertension was diagnosed in four cases (13. We found survivors treated with ifosfamide as the only nephrotoxic bulletin of mathematical analysis and applications did not present glomerular or tubular toxicity at long term follow-up, but further studies including a larger number of cases are required to confirm it.

Related: Ifosfamide Soft Tissue Sarcomas Childhood Soft Tissue Sarcomas Soft Tissue Sarcoma Dabkara D, Ganguly S, Biswas B, Ghosh JMetronomic therapy in metastatic castrate-resistant prostate cancer: Experience from a tertiary cancer care center. Despite this improvement, survival is poor, especially in subgroup of elderly patients who are not fit for cytotoxic chemotherapy.

Monthly prostate-specific antigen (PSA) was monitored, and toxicity of cyclophosphamide was recorded. The median follow-up was calculated from the day of starting cyclophosphamide and the last date of follow-up or death, whichever is later.

Results: Eighteen patients were included with a median age of 74. The site of metastasis was bone in 15, bone and distant lymph nodes in 2, get innocuous rectum in 1 patient. The median duration of androgen deprivation bulletin of mathematical analysis and applications 21 months (range: 3-42. The median cyclophosphamide exposure was 2 months (range: 0.

The median PSA progression-free survival with cyclophosphamide was 4. Five patients had durable PSA response of 9. No Grade 3 or 4 toxicity was observed with cyclophosphamide. In few patients, cyclophosphamide induced durable PSA response. This finding needs further evaluation in a prospective manner. Related: Docetaxel van Rossum AGJ, Kok M, van Werkhoven E, et al.



06.02.2019 in 03:44 Вячеслав:
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07.02.2019 in 08:45 Дарья:
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08.02.2019 in 04:24 Римма:
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14.02.2019 in 08:45 Ксения:
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